What are the side effects of methotrexate injection in Rheumatoid Arthritis?
Methotrexate is a commonly used disease-modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). It is usually administered orally or via injection, and is effective in reducing pain, swelling, and joint damage in patients with RA. However, like all medications, methotrexate is associated with a range of side effects, some of which can be serious. In this article, we will discuss the common and rare side effects of methotrexate injection in rheumatoid arthritis. Common Side Effects of Methotrexate Injection in Rheumatoid Arthritis: 1. Nausea and vomiting: These are the most common side effects of methotrexate. They occur in up to 20% of patients and are usually mild. However, some patients may experience severe nausea and vomiting, which can lead to dehydration and malnutrition. 2. Fatigue: Methotrexate can cause fatigue in up to 20% of patients. This can be due to the drug's effects on the bone marrow, where it can decrease the production of red and ...